Assistant Professor
Watson-Hubbard Science Center 203
Department
STEM
Mailing Address
235 Wellesley Street
Weston, MA 02493
About
About
Before Dr. Xiao joined Regis College faculty in 2013, she has also lectured at School of Arts and Sciences at MCPHS University as adjunct assistant professor and taught at Department of Biology, Boston University as a teaching fellow. She was an instructor and postdoctoral fellow in Neurology at Harvard Medical School/Massachusetts General Hospital and postdoctoral fellow at Department of Psychiatry at Harvard Medical School/New England Primate Center (at Southborough). She is a member of International Society of Magnetic Resonance in Medicine (ISMRM) and Society for Neuroscience.
Research Interests
Functional brain connectivity underlying mechanisms of neurological and psychiatric diseases, and their pharmacological and alternative therapies.
Courses Taught
Undergraduate
- BI 105 Anatomy and Physiology I
- BI 106 Anatomy and Physiology II
- BI 108 Microbiology
- BI 203 Human Biology
- BI 212 Pathophysiology
- BI 306 Neurobiology (with lab)
- ID 224B Interdepartmental Biology (for non-majors)
- BE 250 Quantitative Human Physiology (for Biomedical Engineering Program)
- BI 305 Ecology
- BI 321 Animal Physiology
- BI 410A/409A Independent Study (Biology)
- Neu 403 Independent Study (Neuroscience)
- ID 413 Internship (Alzheimer’s Research)
- BI 305 Ecology
Graduate courses
Education
Doctor of Philosophy (PhD) in Neuroscience, Boston University, 2003
Master of Science in Pharmacology, SUNY Upstate Medical University, 1997
Master of Science in Entomology, Institute of Zoology, Chinese Academy of Science, 1993
Bachelor of Science in Radiologic Sciences, Massachusetts College of Pharmacy and Health Sciences (MCPHS University), 2012
Bachelor of Science in Biology, Henan Normal University, 1990
Awards Honors
Postdoctoral fellowship award from American Parkinson’s Disease Association (APDA), 2006- 2007, Title: “EphA4 in L-DOPA-induced dyskinesia in a mouse model of Parkinson’s disease”.
SMRT John A. Koveleski Award recipient, 2012-2013
Grants
P.I. 7/2021-6/2022, Kaneb Faculty Scholar Grant
Title: “Exploring biomarkers of Alzheimer’s Disease in Monitoring the Disease Progression”
P.I. 7/2020- 6/2021. Kaneb Faculty Scholar Grant
Title: “Mechanisms of Alzheimer’s Disease from a Connection Point of View”
Co-P.I. (Plouffe B., Squeff C.M. and Xiao D.), 6/2016-6/2017
Kaneb Faculty Scholar Grant
Title: “Designing for Student Engagement” at Olin College of Engineering.
Co-P.I. (Consiglio H., Bilozur M., and Xiao, D.), 7/2015-7/2016
Regis College Faculty Development Grant
Title: “Development of an Interdisciplinary Undergraduate Neuroscience Program”
P.I. 9/2006- 9/2007, American Parkinson’s Disease Association (APDA)
Title: “EphA4 in L-DOPA-induced dyskinesia in a mouse model of Parkinson’s disease”. The overall goals addressed whether ephrins are involved in L-DOPA-induced striatal neuroplasticity in an A2A receptor dependent manner.
Publications
Xiao D*., Wang, K*. and Theriault L. White matter changes and key structure affected in Alzheimer’s disease revealed by Diffusion Tension Imaging. European J. Neuroscience 2022; 56(8): 5319-5331; September 8. https://doi.org/10.1111/ejn.15815 (This work was done during the entire pandemic 2020-2021 through online collaboration)
Wang K, Xu C, Theeke LA, Xiao D, Luo X, Xie C. Linear Mixed Model Analysis of Polygenic Hazard Score on Verbal Memory Decline in Alzheimer's Disease. Nurs Res. 2022 Sep 12. doi: 10.1097/NNR.0000000000000623. Epub ahead of print. PMID: 36097266.
Wang K., Lu Y., Morrow DF., Xiao D. and Xu C. Associations of ARHGAP26 polymorphisms with Alzheimer’s Disease and cardiovascular disease. Journal of Molecular Neuroscience 2022; Feb 16. Doi:10.1007/s12031-022-01972-5. Online ahead of print.
Joyce MKP., Marshall LG, Banik SL, Wang J., Xiao D., Bunce JG and Barbas H. Pathways for memory, cognition and emotional context: hippocampal, subgenual area 25 and amygdalar axons show unique interactions in the primate thalamic reuniens nucleus. Journal of Neuroscience. 2022; 42(6):1068-1089
Fokuoh E., Xiao D., Fang W., Liu Y., Lu Y., Wang K-S. 2021 Longitudinal analysis of APOE- ε4 genotype with the logical memory delayed recall score in Alzheimer’s Disease. Journal of Genetics 2021; 160:60
Wang K., Xu C., Smith A., Xiao D., et al 2021 Genome-wide association study identified INSC gene associated with Trail Making Test Part A and Alzheimer’s disease related cognitive phenotypes. Progress in Neuropsychopharmacology & Biological Psychiatry 2021; 111:1-9: doi: 10.1016/j.pnpbp.2021.110393
Black Y*, Xiao D*, Pellegrino D, Kachroo A, Brownell A-L and Schwarzschild M. Protective effect of metabotropic glutamate mGluR5 receptor elimination in a six-hydroxydopamine model of Parkinson’s disease. Neuroscience Letters 2010; 486(3):161-5. (*Co-first author)
Xiao D, Zikoppolos V. and Barbas H. Laminar organization of projections from prefrontal cortex directed to principal and non-principal thalamic nuclei. Neuroscience, 2009; 161(4):1067-81.
Morelli M, Di Paolo T, Wardas J, Calon F, Xiao D. and Schwarzschild MA.2007. Role of adenosine A2A receptors in parkinsonian motor impairment and L-DOPA-induced motor complications. Progress in Neurobiology. 83(5):293-309.
Xiao D, Bastia E, Xu Y-H, Benn CL, Cha J-HJ, Peterson TS, Chen J-F and Schwarzschild MA. Forebrain adenosine A2A receptors contribute to L-DOPA-induced dyskinesia in hemiparkinsonian mice. Journal of Neuroscience 2006; 26(52):13548-55.
Xiao D, Miller G, Jassen A, Westmoreland SV, Pauley D. and Madras BK. Ephrin/Eph receptor expression in brain of adult nonhuman primates: Implications for drug-induced neuroadaptive mechanisms. Brain Research 2006; 1067:67-77.
Jassen AK, Brown JM, Panas HN, Miller G, Xiao D. and Madras BK. Variants of the Primate Vesicular Monoamine Transporter-2. Brain Res. Mol Brain Research 2005; 139:251-7.
Xiao D. and Barbas H. Circuits through prefrontal cortex, ventral anterior nucleus and basal ganglia map pathways beyond motor control. Thalamus and related systems 2004; 2:325-343.
Book Reviews
Morelli M, Di Paolo T, Wardas J, Calon F, Xiao D. and Schwarzschild MA. 2007. Role of adenosine A2A receptors in parkinsonian motor impairment and L-DOPA-induced motor complications. Progress in Neurobiology. 83(5):293-309.
Barbas H, Ghashghaei HT, Rempel-Clower and Xiao D. Anatomic basis of functional specialization in prefrontal cortices in primates. In: Grafman, J. editor. Handbook of Neuropsychology, Second Edition. Amsterdam: Elsevier Science Publishers; 2002. Vol. 7. p.1-27.
Xiao, D. 2015. Acupuncture for Parkinson’s Disease –A review of clinical, animal and fMRI studies. Journal of Traditional Chinese Medicine. 35(6):709-717.
